2,6-Dichloro-N-phenylpyrimidin-4-amine CAS 28230-47-9
| CAS No. | 28230-47-9 |
| Molecular Formula | C10H7Cl2N3 |
| Molecular Weight | 240.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,6-Dichloro-N-phenylpyrimidin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,6-Dichloro-N-phenylpyrimidin-4-amine (CAS 28230-47-9) is a high-purity analytical reference standard with the molecular formula C10H7Cl2N3 and a molecular weight of 240.09 g/mol.
The molecular framework of 2,6-Dichloro-N-phenylpyrimidin-4-amine (C10H7Cl2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N3 |
| Molecular Weight | 240.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 4,6-dichloro-5-methyl-2-(pyridin-2-yl)pyrimidine (CAS 10198-77-3)
- 1,1-Dichloro-1,2-dihydrocyclobuta[c]quinolin-3(4H)-one (CAS 111736-16-4)
- 6,8-dichloro-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1221723-95-0)
- 4,5-Dichloro-6-methyl-2-(pyridin-4-yl)pyrimidine (CAS 1239850-50-0)
- 2,7-Dichloro-8-methylquinoline-3-carbaldehyde (CAS 131923-69-8)
- 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (CAS 1638760-72-1)
- 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid (CAS 1638768-02-1)
- 2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine-6-carboxylic acid (CAS 1781241-35-7)
Recommended Standards
- 2,4-Dichloro-N-(furan-2-ylmethylene)aniline (CAS 81335-99-1)
- 2-Benzyl-4,6-dichloro-1,3,5-triazine (CAS 26650-79-3)
- 1-Chloro-4-methylisoquinoline-3-carbonyl chloride (CAS 89928-57-4)
- 2-Chloro-N-(3-chlorophenyl)pyrimidin-4-amine (CAS 260045-66-7)
- (E)-4-(3-(thiophen-2-yl)acryloyl)phenyl 4-bromobenzenesulfonate (CAS 297150-18-6)
- 1,1-Dichlorocyclohexane (CAS 2108-92-1)
- 4-(Difluoromethyl)-2-iodo-3-nitro-5-(trifluoromethoxy)pyridine (CAS 1804360-40-4)
- 2-Amino-5-ethyl-6-(o-tolylamino)pyrimidin-4(1H)-one (CAS 6327-20-4)
- 2-(4-Aminobenzyl)-1H-benzo[d]imidazol-5-amine (CAS 110182-56-4)
- 2-((4,6-Dimethylpyrimidin-2-yl)thio)-N-(4-iodophenyl)acetamide (CAS 298217-99-9)
- Ethyl 5-(4-fluorophenoxy)pentanoate (CAS 418810-85-2)
- NDSB-221 (CAS 160788-56-7)
- Methyl 5-hydroxy-2-naphthoate (CAS 188861-83-8)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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