7-Bromo-2,4-dichloro-6-(difluoromethoxy)-8-fluoroquinazoline CAS 2823478-23-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2823478-23-3
Molecular FormulaC9H2BrCl2F3N2O
Molecular Weight361.93 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Bromo-2,4-dichloro-6-(difluoromethoxy)-8-fluoroquinazoline CAS 2823478-23-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Bromo-2,4-dichloro-6-(difluoromethoxy)-8-fluoroquinazoline.

7-Bromo-2,4-dichloro-6-(difluoromethoxy)-8-fluoroquinazoline (CAS 2823478-23-3), molecular formula C9H2BrCl2F3N2O and molecular weight 361.93 g/mol, is a CATO reference standard with documented purity and traceability.

7-Bromo-2,4-dichloro-6-(difluoromethoxy)-8-fluoroquinazoline (C9H2BrCl2F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 7-Bromo-2,4-dichloro-6-(difluoromethoxy)-8-fluoroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H2BrCl2F3N2O
Molecular Weight361.93 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms2

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