(4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanamine CAS 282520-55-2

Description

The occurrence of (4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanamine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanamine (CAS 282520-55-2), molecular formula C10H14N2O and molecular weight 178.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanamine (C10H14N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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