(5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl 3-chlorobenzoate CAS 282523-62-0
| CAS No. | 282523-62-0 |
| Molecular Formula | C13H9Cl2F3N2O2 |
| Molecular Weight | 353.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl 3-chlorobenzoate.
CATO supplies (5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl 3-chlorobenzoate (CAS 282523-62-0), a certified reference material (molecular formula C13H9Cl2F3N2O2, MW 353.12 g/mol) for analytical method development and quality control.
The molecular framework of (5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl 3-chlorobenzoate (C13H9Cl2F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9Cl2F3N2O2 |
| Molecular Weight | 353.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- (5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl 4-chlorobenzoate (CAS 282523-34-6)
- 2-Chloro-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6-nitrophenol (CAS 882747-86-6)
- N5-(3-chloro-4-fluorophenyl)-4-chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide (CAS 649665-04-3)
- 4-Chloro-N-(2-(4-chlorobenzamido)ethoxy)benzamide (CAS 338413-95-9)
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- 2-Chloro-N-[4-chloro-3-(morpholine-4-sulfonyl)phenyl]acetamide (CAS 379254-82-7)
- 4-Chloro-1-(2-chloro-2-phenylethyl)-6-(ethylthio)-1H-pyrazolo[3,4-d]pyrimidine (CAS 679805-52-8)
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Recommended Standards
- 5-(4-Iodophenyl)-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione (CAS 1204298-61-2)
- 5-Iodo-2-deoxycytidine (CAS 611-53-0)
- 6-Methyl-3-nitro-2-oxo-1,2-dihydropyridin-4-yl 2-bromobenzoate (CAS 868679-76-9)
- 1-((2R,4S,5R)-5-(Aminomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione (CAS 56045-73-9)
- 1-(Difluoromethyl)-2-oxo-1,2-dihydropyridine-4-carbaldehyde (CAS 2168703-41-9)
- 5-chloro-7-methyl-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 72411-32-6)
- 2-[(4-fluorophenyl)methyl]piperidine (CAS 67157-30-6)
- (S)-4-((R)-Sec-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole (CAS 1620588-66-0)
- 1,3-Dibromo-5-(2-ethylhexyl)-4H-thieno[3,4-c]pyrrole-4,6(5H)-dione (CAS 1231160-83-0)
- [1,3]Dioxolo[4,5-b]pyridin-6-ylmethanamine (CAS 1260671-81-5)
- N-benzyl-1-(5-methylfuran-2-yl)methanamine (CAS 130539-99-0)
- 1437794-82-5 C13H15BrN2O2 Ethyl 7-bromo-1-ethyl-2-methyl-1,3-benzodiazole-5-carboxylate V3297 (CAS 1437794-82-5)
- Ethyl 3-oxopiperidine-1-carboxylate (CAS 61995-19-5)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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