2-(4-Fluorobenzylidene)malononitrile CAS 2826-22-4
| CAS No. | 2826-22-4 |
| Molecular Formula | C10H5FN2 |
| Molecular Weight | 172.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 172.16 g/mol gives 2-(4-Fluorobenzylidene)malononitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(4-Fluorobenzylidene)malononitrile (CAS 2826-22-4) is a high-purity analytical reference standard with the molecular formula C10H5FN2 and a molecular weight of 172.16 g/mol.
The molecular framework of 2-(4-Fluorobenzylidene)malononitrile (C10H5FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-Fluorobenzylidene)malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5FN2 |
| Molecular Weight | 172.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorobenzylidene Standards
- 2-(2-Fluorobenzylidene)malononitrile (CAS 2698-43-3)
- 2-(3-Fluorobenzylidene)malononitrile (CAS 2972-71-6)
- N-(2-Fluorobenzylidene)-2-methylpropan-2-amine (CAS 195004-63-8)
- 3-(4-Fluorobenzylidene)azetidine (CAS 1502038-83-6)
- 3-(2-Fluorobenzylidene)azetidine (CAS 1517659-55-0)
- 3-(3-Fluorobenzylidene)azetidine (CAS 1521916-55-1)
- 4-(2-Fluorobenzylidene)oxazol-5(4H)-one (CAS 89242-25-1)
- 4-(2-Fluorobenzylidene)piperidine (CAS 676490-76-9)
Recommended Standards
- 2-Fluoroquinoline-4-carbonitrile (CAS 50504-19-3)
- 2-Imino-4-oxo-3,4-dihydro-2H-1,3-thiazine-6-carboxylic acid (CAS 24331-17-7)
- 1-Ethyl-4-fluoro-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 2243003-72-5)
- 2-Oxo-2-(thiazol-2-ylamino)acetic acid (CAS 6890-84-2)
- (3-Bromo-4-methoxy-5-nitrophenyl)methanol (CAS 2386434-21-3)
- N4,N4'-Bis(9-(naphthalen-2-yl)-9H-carbazol-3-yl)-N4,N4'-diphenyl-[1,1'-biphenyl]-4,4'-diamine (CAS 934545-87-6)
- Ruthenium(2+), bis(acetonitrile)bis[1,3-dihydro-1-(2-pyridinyl-κN)-3-(2,4,6-trimethylphenyl)-2H-imidazol-2-ylidene-κC]-, (OC-6-33)-, hexafluorophosphate(1-) (1:2) (CAS 2088512-45-0)
- Dexrazoxane Impurity 44 (CAS 21416-67-1)
- 5-Nitrosopyrimidine-4,6-diamine (CAS 61908-15-4)
- 4'-Hydroxy Atomoxetine-d3 (CAS 1217686-14-0)
- 1-(4-Fluorophenyl)-6-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1094377-62-4)
- 7-Bromo-5-fluoroindoline (CAS 1156704-69-6)
- N,N-Dimethyl-1H-indene-2-ethanamine-d6 Hydrochloride (CAS 1346604-85-0)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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