4-Chloro-3-(1,3-dioxolan-2-yl)-2-fluoropyridine CAS 2832065-91-3
| CAS No. | 2832065-91-3 |
| Molecular Formula | C8H7ClFNO2 |
| Molecular Weight | 203.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-(1,3-dioxolan-2-yl)-2-fluoropyridine.
4-Chloro-3-(1,3-dioxolan-2-yl)-2-fluoropyridine (CAS 2832065-91-3) is a high-purity analytical reference standard with the molecular formula C8H7ClFNO2 and a molecular weight of 203.60 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-Chloro-3-(1,3-dioxolan-2-yl)-2-fluoropyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 203.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-3-(1,3-dioxolan-2-yl)-2-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClFNO2 |
| Molecular Weight | 203.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Ethyl 4-chloro-5-fluoronicotinate (CAS 1009334-54-6)
- Methyl 4-chloro-5-fluoroanthranilate (CAS 104901-79-3)
- N'-(5-Chloro-3-fluoropyridin-2-yl)acetohydrazide (CAS 1150561-82-2)
- N-(4-chloro-2-fluorophenyl)-2-hydroxyacetamide (CAS 1155534-62-5)
- Ethyl 2-chloro-3-fluoro-5-pyridinecarboxylate (CAS 1214332-76-9)
- Ethyl 2-chloro-6-fluoroisonicotinate (CAS 1214332-80-5)
- 5-Chloro-2-fluoronicotinic acid ethyl ester (CAS 1214345-81-9)
- Ethyl 2-chloro-5-fluoroisonicotinate (CAS 1214346-94-7)
Recommended Standards
- 3-Fluoro-n-hydroxy-4-methoxybenzene-1-carbonimidoyl chloride (CAS 677728-80-2)
- 5-Amino-2-chloro-4-fluoro-3-methylbenzoic acid (CAS 2019193-67-8)
- 3-Chloro-5-fluoro-4-methoxybenzamide (CAS 886497-40-1)
- 6-Chloro-2-fluoro-3-methoxybenzamide (CAS 886761-75-7)
- 4-Chloro-[1,2,5]thiadiazolo[3,4-c]pyridine (CAS 26271-17-0)
- 2-(4-Ethylpiperazin-1-yl)-5-(trifluoromethyl)aniline (CAS 937596-13-9)
- 1,3-Dimethyl-2,4-dioxo-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-7-carboxylic acid (CAS 1000932-76-2)
- FCN437 Impurity 1 (CAS 1665-65-2)
- (S)-1-(3-bromo-5-methylphenyl)-2-methylpropan-1-amine (CAS 1270278-78-8)
- 2-(1,2-Dimethyl-1H-indol-3-yl)-ethylaminehydrochloride (CAS 113772-31-9)
- N-Cbz-3(S)-fluoropyrrolidine (CAS 136725-52-5)
- Avibactam Impurity 6(2S,5S) (CAS CATO-C4X-13486)
- 6-Bromo-7-(methoxymethyl)imidazo[1,2-a]pyridine (CAS 2791313-90-9)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com