Sildenafil Impurity 72 CAS 2840532-32-1
| CAS No. | 2840532-32-1 |
| Molecular Formula | C24H34N6O4S |
| Molecular Weight | 502.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Sildenafil Impurity 72 (C24H34N6O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 502.63 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Sildenafil Impurity 72 (CAS 2840532-32-1, C24H34N6O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H34N6O4S |
| Molecular Weight | 502.63 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Sildenafil Standards
- Sildenafil Impurity 29 (CAS 1093065-15-6)
- Sildenafil impurity 249 (CAS CATO-C4X-1128249)
- Sildenafil Impurity 252 (CAS CATO-C4X-1128252)
- Sildenafil Impurity C31 (CAS 2196244-90-1)
- Sildenafil Impurity 267 (CAS 2305789-77-7)
- Sildenafil Impurity 89 (CAS 2520113-03-3)
- Sildenafil Impurity 304 (CAS CATO-C4X-1128304)
- Sildenafil Impurity 23 (CAS 200575-15-1)
Recommended Standards
- O-Desethyl-O-propyl Methisosildenafil (CAS 1391053-82-9)
- Vardenafil Impurity 42 (CAS CATO-C4X-101742)
- 2,3-Dihydro-7-(Trifluoromethyl)-4H-1,2,4-Benzothiadiazine-4-Ethanol 1,1-Dioxide (CAS 1789-84-0)
- Vardenafil Impurity 41 (CAS CATO-C4X-101741)
- Tramadol EP Impurity D ( and Enantiomer)Hydrochloride (CAS 80456-81-1(free base))
- Landiolol Impurity 84 HCl (CAS CATO-C4X-262184)
- Allisartan Isoproxil Impurity 27 (CAS 947331-07-9)
- 2-(4-Cyclohexylphenyl)-6-fluoro-3-methylquinoline-4-carboxylic acid (CAS 96187-26-7)
- (3,5-DIMETHOXYPHENYL)METHANOL 3,5-Dimethoxybenzyl alcohol 705-76-0 AS03975 RARECHEM AL BD 0065 (CAS 705-76-0)
- 2-Propenoic acid, 2-methyl-, 2-(3-oxazolidinyl)ethyl ester (CAS 46235-93-2)
- N-(2-cyclobutylethyl)-2-methylpropan-2-amine (CAS 1485147-98-5)
- 5-Methyl-6-(methyl(phenyl)amino)nicotinonitrile (CAS 1355218-07-3)
- Promethazine Impurity 29 (CAS 20962-92-9)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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