1-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile CAS 28448-08-0

Purity 97%+In StockPharmaceutical Standards
CAS No.28448-08-0
Molecular FormulaC11H8N2O
Molecular Weight184.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile CAS 28448-08-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile.

CATO supplies 1-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile (CAS 28448-08-0), a certified reference material (molecular formula C11H8N2O, MW 184.19 g/mol) for analytical method development and quality control.

1-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile (C11H8N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-Methyl-2-oxo-1,2-dihydroquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H8N2O
Molecular Weight184.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1965
Nitrogen Atoms2

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