N-(tert-Butyl)-2-nitroaniline CAS 28458-45-9
| CAS No. | 28458-45-9 |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(tert-Butyl)-2-nitroaniline.
N-(tert-Butyl)-2-nitroaniline (CAS 28458-45-9) is a high-purity analytical reference standard with the molecular formula C10H14N2O2 and a molecular weight of 194.23 g/mol.
The molecular framework of N-(tert-Butyl)-2-nitroaniline (C10H14N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(tert-Butyl)-2-nitroaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
Recommended Standards
- n-(Sec-butyl)-4-nitroaniline (CAS 4138-37-8)
- N-(tert-Butyl)-4-nitroaniline (CAS 4138-38-9)
- n-(Sec-butyl)-2-nitroaniline (CAS 55432-21-8)
- N,N-Diethyl-m-nitroaniline (CAS 2216-16-2)
- 5,6-Dimethoxy-2-methylisoindoline (CAS 114041-11-1)
- 5-Chloro-4'-formyl-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261929-46-7)
- (5-(3-((tert-Butoxycarbonyl)amino)propanamido)pyridin-3-yl)boronic acid (CAS 1171897-31-6)
- Isomogroside V (CAS 1126032-65-2)
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Why CATO?
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