N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide CAS 284664-78-4

Purity 97%+In StockPharmaceutical Standards
CAS No.284664-78-4
Molecular FormulaC8H4ClF4NO
Molecular Weight241.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide CAS 284664-78-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide.

N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide (CAS 284664-78-4) is a high-purity analytical reference standard with the molecular formula C8H4ClF4NO and a molecular weight of 241.57 g/mol.

Structurally, N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide (C8H4ClF4NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 241.57 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N1-(2,4-difluorophenyl)-2-chloro-2,2-difluoroacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H4ClF4NO
Molecular Weight241.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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