tert-Butyl 2-iodo-5-azaspiro[3.4]octane-5-carboxylate CAS 2852761-35-2
| CAS No. | 2852761-35-2 |
| Molecular Formula | C12H20INO2 |
| Molecular Weight | 337.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 337.20 g/mol gives tert-Butyl 2-iodo-5-azaspiro[3.4]octane-5-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
tert-Butyl 2-iodo-5-azaspiro[3.4]octane-5-carboxylate (CAS 2852761-35-2) is a high-purity analytical reference standard with the molecular formula C12H20INO2 and a molecular weight of 337.20 g/mol.
The molecular framework of tert-Butyl 2-iodo-5-azaspiro[3.4]octane-5-carboxylate (C12H20INO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl 2-iodo-5-azaspiro[3.4]octane-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20INO2 |
| Molecular Weight | 337.20 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (6-iodospiro[3.3]heptan-2-yl)carbamate (CAS 2852761-38-5)
- tert-Butyl 2-iodo-6-azaspiro[3.4]octane-6-carboxylate (CAS 2681279-36-5)
- rel-tert-Butyl(3aR,6aS)-5-iodohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (CAS 2853443-57-7)
- tert-butyl 3-iodo-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 2674113-13-2)
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- Peptide Impurity 06 (CAS CATO-CPTD788806)
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