rel-(3R,4R)-4-(2,2-Difluoroethoxy)tetrahydrofuran-3-amine hydrochloride CAS 2853616-55-2
| CAS No. | 2853616-55-2 |
| Molecular Formula | C6H11F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of rel-(3R,4R)-4-(2,2-Difluoroethoxy)tetrahydrofuran-3-amine hydrochloride (C6H11F2NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
rel-(3R,4R)-4-(2,2-Difluoroethoxy)tetrahydrofuran-3-amine hydrochloride (CAS 2853616-55-2), molecular formula C6H11F2NO2HCl and molecular weight 203.61 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), rel-(3R,4R)-4-(2,2-Difluoroethoxy)tetrahydrofuran-3-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H11F2NO2 HCl |
| Molecular Weight | 203.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 5-Bromo-6-ethylpyrimidin-4-amine (CAS 1520502-87-7)
- 2-Chloro-5-methoxyisonicotinaldehyde (CAS 1060801-65-1)
- (R)-3-Amino-3-(pyridin-2-yl)propanamide (CAS 1213481-96-9)
- (5,5-Dimethyl-1,3-dioxan-2-yl)methanol (CAS 913695-80-4)
- Lacto-N-difucohexaose I (CAS 16789-38-1)
- N-(2-(benzyloxy)benzyl)thietan-3-amine (CAS 2003163-24-2)
- 1-(3-Cyanophenyl)-3-isopropyl-1h-pyrazole-5-carboxylic acid (CAS 1012879-75-2)
- 1-(2,4,5-Trimethyl-1H-pyrrol-3-yl)ethan-1-one (CAS 19005-95-9)
- Lacosamide Impurity 31 (CAS 1629130-53-5)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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