3-(Chloromethyl)-5-phenyl-1H-1,2,4-triazole CAS 28563-75-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Chloromethyl)-5-phenyl-1H-1,2,4-triazole.

3-(Chloromethyl)-5-phenyl-1H-1,2,4-triazole (CAS 28563-75-9), molecular formula C9H8ClN3 and molecular weight 193.63 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(Chloromethyl)-5-phenyl-1H-1,2,4-triazole (C9H8ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(Chloromethyl)-5-phenyl-1H-1,2,4-triazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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