Adefovir Dipivoxil Impurity 18 CAS 2857-97-8

Description

The occurrence of Adefovir Dipivoxil Impurity 18 is closely related to bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Adefovir Dipivoxil Impurity 18 (CAS 2857-97-8), a certified reference material (molecular formula C3H9BrSi, MW 153.09 g/mol) for analytical method development and quality control.

The molecular framework of Adefovir Dipivoxil Impurity 18 (C3H9BrSi) is characterized by bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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