5-Chloro-2,6-dimethylpyrimidin-4-amine CAS 2858-20-0
| CAS No. | 2858-20-0 |
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-2,6-dimethylpyrimidin-4-amine (C6H8ClN3) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-Chloro-2,6-dimethylpyrimidin-4-amine (CAS 2858-20-0), molecular formula C6H8ClN3 and molecular weight 157.60 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2,6-dimethylpyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8ClN3 |
| Molecular Weight | 157.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-N2-methylpyridine-2,3-diamine (CAS 100114-37-2)
- 4-Chloro-3-ethoxypyridine (CAS 1003711-81-6)
- 5-Chloro-2,3-dimethylpyridine 1-oxide (CAS 1015057-46-1)
- 2-Chloro-5-(methoxymethyl)pyridine (CAS 1016534-59-0)
- 3-Chloro-5-methoxyaniline (CAS 10272-06-7)
- 3-Chloro-5-(methylamino)phenol (CAS 1082113-30-1)
- (6-Chloro-2-methylpyridin-3-yl)methanol (CAS 1093879-95-8)
- 2-Chloro-4-methoxy-5-methylpyridine (CAS 1122090-84-9)
Recommended Standards
- 5-(Aminomethyl)-2-chlorophenol (CAS 943816-63-5)
- 5-Chloro-2-ethoxypyridine (CAS 22109-30-4)
- 4-Chloro-N-ethylpyrimidin-5-amine (CAS 873686-90-9)
- 5-Chloro-2-hydroxylaminotoluene (CAS 71259-54-6)
- N-methyloctahydro-1H-indole-2-carboxamide (CAS 1103184-37-7)
- 7-Amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 387361-34-4)
- (2R,4S)-2-Ethyl-4-(3-(trimethylsilyl)propyl)cyclopentanone (CAS 507235-62-3)
- 6-Ethyl-2-(m-tolyl)quinoline-4-carboxylic acid (CAS 861453-64-7)
- 1-(4-Methyl-1,3-thiazol-2-yl)cyclopentan-1-amine (CAS 1181234-20-7)
- 4-(4-(Allyloxy)benzoyl)-5-(2-fluorophenyl)-3-hydroxy-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 618074-23-0)
- 3-Bromo-7,8-difluoroquinoline (CAS 1686108-69-9)
- 7-Methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2(1H)-thione (CAS 100114-29-2)
- Tert-butyl N-(azepan-4-yl)-N-methylglycinate (CAS 1803582-24-2)
- Anxiety Peptide (CAS 95237-86-8)
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