1-(2-Hydroxy-3-tosylpropyl)pyrrolidin-2-one CAS 285986-61-0
| CAS No. | 285986-61-0 |
| Molecular Formula | C14H19NO4S |
| Molecular Weight | 297.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Hydroxy-3-tosylpropyl)pyrrolidin-2-one.
1-(2-Hydroxy-3-tosylpropyl)pyrrolidin-2-one (CAS 285986-61-0) is a high-purity analytical reference standard with the molecular formula C14H19NO4S and a molecular weight of 297.37 g/mol.
1-(2-Hydroxy-3-tosylpropyl)pyrrolidin-2-one (C14H19NO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19NO4S |
| Molecular Weight | 297.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
- 1-(2-Hydroxy-3-phenylmethanesulfonylpropyl)pyrrolidin-2-one (CAS 285986-97-2)
- 3-Benzyl-4-hydroxy-1-(thiophen-2-ylmethyl)pyridin-2(1H)-one (CAS 477868-49-8)
- 9-Hydroxy-11-thia-1-azatetracyclo[10.7.0.0^{3,8}.0^{13,18}]nonadeca-3(8),4,6,13(18),14,16-hexaen-19-one (CAS 866008-85-7)
- N-Hydroxy-11-azaartemisinin (CAS 1086409-82-6)
- (4'-Hydroxy-3'-methoxy-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261931-57-0)
- (3'-Hydroxy-4'-methoxy-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261968-71-1)
- 4-(5-(Hydroxy(phenyl)methyl)pyridin-2-yl)piperazine-1-carbaldehyde (CAS 1355237-30-7)
- 6'-Hydroxy-5'-methoxy-1'-methyl-2',3',8',8a'-tetrahydro-1'H-spiro[cyclohexa[2,5]diene-1,7'-cyclopenta[ij]isoquinolin]-4-one (CAS 17127-48-9)
Recommended Standards
- 1-(3,4-Dimethylbenzenesulfonyl)piperidine-4-carboxylic acid (CAS 727983-31-5)
- 1-(2,4-Dimethylbenzenesulfonyl)piperidine-4-carboxylic acid (CAS 757192-81-7)
- 1-(4-Methylbenzenesulfonyl)piperidine-3-carbohydrazide (CAS 312286-45-6)
- 1-(1H-Benzo[d][1,2,3]triazol-1-yl)-3-(p-tolylthio)propan-2-one (CAS 305861-12-5)
- 5-(Aminomethyl)-3-methyloxazolidin-2-one hydrochloride (CAS 1432679-93-0)
- Tert-butyl 4-(diethylamino)piperidine-1-carboxylate (CAS 1281634-35-2)
- Ethyl 7-hydroxybenzofuran-5-carboxylate (CAS 831222-95-8)
- Selegiline EP Impurity E (CAS 4528-51-2)
- (1-(3-Methoxy-4-methylphenyl)cyclobutyl)methanamine (CAS 1037131-87-5)
- Famotidine impurity 76 (CAS CATO-C4X-139276)
- 1-(3-Bromopropyl)-3-nitrobenzene (CAS 1823-16-1)
- 4-Methyl-1-(pyridin-2-yl)pentan-1-amine (CAS 1249698-52-9)
- 4-[(4-Chlorobenzyl)amino]benzohydrazide (CAS 439093-68-2)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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