2-(1-Chloroethyl)thiophene CAS 28612-98-8
| CAS No. | 28612-98-8 |
| Molecular Formula | C6H7ClS |
| Molecular Weight | 146.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1-Chloroethyl)thiophene.
CATO supplies 2-(1-Chloroethyl)thiophene (CAS 28612-98-8), a certified reference material (molecular formula C6H7ClS, MW 146.64 g/mol) for analytical method development and quality control.
2-(1-Chloroethyl)thiophene (C6H7ClS) contains sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7ClS |
| Molecular Weight | 146.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloroethyl Standards
- (1-Chloroethyl)cyclohexane (CAS 1073-43-4)
- (2-Chloroethyl)cyclohexane (CAS 1073-61-6)
- 5-(2-chloroethyl)-1-methyl-1H-1,2,3,4-tetrazole (CAS 15284-37-4)
- 5-(1-chloroethyl)-1-methyl-1H-1,2,3,4-tetrazole (CAS 186958-71-4)
- 3-(1-chloroethyl)-5-methyl-1,2,4-oxadiazole (CAS 1595727-51-7)
- 1-(2-Chloroethyl)-1H-imidazol-2-ol (CAS 938459-07-5)
- 2-(1-chloroethyl)-5-methyl-1,3,4-oxadiazole (CAS 926207-51-4)
- 3-(2-chloroethyl)-5-methyl-1,2,4-oxadiazole (CAS 71088-13-6)
Recommended Standards
- 2-(Chloromethyl)-4-methylthiophene (CAS 1260667-87-5)
- 2-(Chloromethyl)-3-methylthiophene (CAS 92521-25-0)
- 3-(Chloromethyl)-2-methylthiophene (CAS 116608-03-8)
- 2-(Chloromethyl)-5-methylthiophene (CAS 34776-73-3)
- Ethyl 2-chloro-6-methylpyrimidine-4-carboxylate (CAS 265328-14-1)
- 2-(3-Chloro-4-fluorophenoxy)ethan-1-amine (CAS 883524-07-0)
- Phenyl(thiophen-2-yl)methanamine (CAS 5693-42-5)
- 4,6-Dimethyl-3-(4-methylbenzenesulfonyl)-2-[3-(trifluoromethyl)phenoxy]pyridine (CAS 478245-36-2)
- 3-Neopentylpyrrolidine (CAS 1337112-03-4)
- 4-(Methylamino)-4-(3-pyridyl)butyric Acid (CAS 15569-99-0)
- 4-(2,6-Difluorobenzoyl)-N-(3-(trifluoromethyl)benzyl)-1H-pyrrole-2-carboxamide (CAS 439112-13-7)
- 3-[(4-methylphenyl)sulfamoyl]thiophene-2-carboxylic acid (CAS 944894-01-3)
- 1-(4-(Decyloxy)phenyl)ethan-1-one (CAS 18099-59-7)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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