1-(2,6-Difluoro-4-iodopyridin-3-yl)ethan-1-one CAS 2863532-63-0

Purity 97%+In StockPharmaceutical Standards
CAS No.2863532-63-0
Molecular FormulaC7H4F2INO
Molecular Weight283.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,6-Difluoro-4-iodopyridin-3-yl)ethan-1-one CAS 2863532-63-0 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

1-(2,6-Difluoro-4-iodopyridin-3-yl)ethan-1-one (CAS 2863532-63-0), molecular formula C7H4F2INO and molecular weight 283.01 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2,6-Difluoro-4-iodopyridin-3-yl)ethan-1-one (C7H4F2INO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC7H4F2INO
Molecular Weight283.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF/I-containing
Nitrogen Atoms1

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