4-(((6-Amino-3-(4-chlorophenyl)pyrido[2,3-b]pyrazin-8-yl)amino)methyl)benzenesulfonamide CAS 28643-00-7
| CAS No. | 28643-00-7 |
| Molecular Formula | C20H17ClN6O2S |
| Molecular Weight | 440.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(((6-Amino-3-(4-chlorophenyl)pyrido[2,3-b]pyrazin-8-yl)amino)methyl)benzenesulfonamide (C20H17ClN6O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(((6-Amino-3-(4-chlorophenyl)pyrido[2,3-b]pyrazin-8-yl)amino)methyl)benzenesulfonamide (CAS 28643-00-7), molecular formula C20H17ClN6O2S and molecular weight 440.91 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17ClN6O2S |
| Molecular Weight | 440.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Amino Standards
- (3-Amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone (CAS 94360-99-3)
- (E)-2-amino-3-((4-((2-chloro-6-fluorobenzyl)oxy)benzylidene)amino)-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 866149-01-1)
- N-(2-Amino-4-chlorobenzo[d]thiazol-6-yl)-2-(2-bromo-4,6-dimethylphenoxy)acetamide (CAS 1706452-40-5)
- Ethyl 5-amino-4-iodo-1-(4-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate (CAS 1427023-89-9)
- (S)-6-Amino-5-(1-(4-(benzyloxy)-3-methoxyphenyl)-2-nitroethyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (CAS 736948-88-2)
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(2,2,2-trifluoroacetamido)benzamide (CAS 102587-85-9)
- 3-Amino-N-(2,4-difluorophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626227-43-8)
- 2-((S)-5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)-3-phenylpropanoic Acid Methyl Ester (CAS 14317-85-2)
Recommended Standards
- 1,1',1''-(Benzene-1,3,5-triyl)tris(2-bromoethanone) (CAS 38460-56-9)
- 7-(4-Chlorophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1226430-85-8)
- Glipizide Impurity 34 (CAS 14511-59-2)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-7-(3-fluorophenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1243004-67-2)
- 1-Bromo-2-prop-2-enylsulfanylbenzene (CAS 154180-30-0)
- 1-Benzyl 4-ethyl 2-carbamoylpiperidine-1,4-dicarboxylate (CAS 1251844-34-4)
- 2-(2,3-Dibromo-6-ethoxy-4-formylphenoxy)acetamide (CAS 832673-96-8)
- 2-(4-tert-Butylbenzoyl)-5-methylpyridine (CAS 1187170-19-9)
- 5-Bromo-2-chlorobenzo[d]thiazole (CAS 824403-26-1)
- DL-Dithiothreitol (CAS 3483-12-3)
- (R)-2-((tert-Butoxycarbonyl)amino)-5-phenylpentanoic acid (CAS 156130-68-6)
- Delafloxacin Impurity 21 (CAS CATO-C4X-263721)
- Sodium 5-bromo-4-methyl-1,3-thiazole-2-carboxylate (CAS 2138517-32-3)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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