Letermovir impurity 119 CAS 2864441-61-0
| CAS No. | 2864441-61-0 |
| Molecular Formula | C36H34F4N4O4 |
| Molecular Weight | 662.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Letermovir impurity 119.
Letermovir impurity 119 (CAS 2864441-61-0) is a certified pharmaceutical impurity reference standard with the molecular formula C36H34F4N4O4 and a molecular weight of 662.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Letermovir impurity 119 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 662.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Letermovir impurity 119 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C36H34F4N4O4 |
| Molecular Weight | 662.67 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Letermovir Standards
- Letermovir impurity 118 (CAS 2758792-75-3)
- Letermovir Impurity 120 (CAS CATO-C4X-2915120)
- Letermovir Impurity 36 (CAS CATO-C4X-291536)
- Letermovir Impurity 32 (CAS 2994645-03-1)
- (R)-Letermovir Ethyl Ester (CAS CATO-C4X-291535)
- Letermovir Impurity 41 (CAS CATO-C4X-291541)
- Letermovir Impurity 24 (CAS CATO-C4X-291524)
- Letermovir Impurity 23 (CAS CATO-C4X-291523)
Recommended Standards
- Azadirachtin H (CAS 134788-15-1)
- 7,12-Bis(2,2-Difluoroethenyl)-3,8,13,17-Tetramethyl-21H,23H-Porphine-2,18-Dipropanoic Acid Dimethyl Ester (CAS 123279-53-8)
- Flomoxef Impurity 17 (CAS 949587-46-6)
- 4,4',4''-(((Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))tris(methylene))tribenzoic acid (CAS 1093949-56-4)
- Osimertinib Impurity 65 (CAS CATO-C4X-204565)
- Cefdinir Impurity 33 (CAS CATO-C4X-121033)
- Atrasentan Impurity 56 (CAS 1063836-14-5)
- N-(3-aminophenyl)-3-chlorobenzamide (CAS 293737-89-0)
- 1-Benzyl-4-(2-chlorophenoxy)piperidine (CAS 900512-07-4)
- 5-[4,2′:6′,4′′-Terpyridin]-4′-yl-1,3-benzenedicarboxylic acid (CAS 1610059-51-2)
- (1S,6R)-8-methyl-3,8-diazabicyclo[4.2.0]Octane bis(2,2,2-trifluoroacetate) (CAS 2227198-51-6)
- Oxomemazine Impurity 2 HCl (CAS 31412-48-3)
- ((1R,2R)-2-(4-iodophenyl)cyclopropyl)methanol (CAS 1678527-90-6)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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