6-Bromo-5-fluorobenzofuran CAS 286837-12-5
| CAS No. | 286837-12-5 |
| Molecular Formula | C8H4BrFO |
| Molecular Weight | 215.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Bromo-5-fluorobenzofuran is closely related to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Bromo-5-fluorobenzofuran (CAS 286837-12-5) is a high-purity analytical reference standard with the molecular formula C8H4BrFO and a molecular weight of 215.02 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 6-Bromo-5-fluorobenzofuran is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 215.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Bromo-5-fluorobenzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4BrFO |
| Molecular Weight | 215.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
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