Methyl 2-(4,5-Dichloro-2-nitrophenyl)acetate CAS 286949-63-1
| CAS No. | 286949-63-1 |
| Molecular Formula | C9H7Cl2NO4 |
| Molecular Weight | 264.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-(4,5-Dichloro-2-nitrophenyl)acetate.
CATO supplies Methyl 2-(4,5-Dichloro-2-nitrophenyl)acetate (CAS 286949-63-1), a certified reference material (molecular formula C9H7Cl2NO4, MW 264.06 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 2-(4,5-Dichloro-2-nitrophenyl)acetate (C9H7Cl2NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl2NO4 |
| Molecular Weight | 264.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Ethyl 2,4-dichloro-5-nitrobenzoate (CAS 101724-08-7)
- Ethyl 2,6-dichloro-4-nitrobenzoate (CAS 1397191-74-0)
- 3-(4,5-dichloro-2-nitrophenyl)propanoic acid (CAS 1416373-98-2)
- 2,4-Dichloro-6-(difluoromethoxy)quinoline (CAS 1422496-25-0)
- Ethyl 3,4-dichloro-2-nitrobenzoate (CAS 1803726-97-7)
- Ethyl 2,4-dichloro-6-nitrobenzoate (CAS 1803837-37-7)
- Ethyl 2,3-dichloro-6-nitrobenzoate (CAS 1804897-35-5)
- Ethyl 2,5-dichloro-4-nitrobenzoate (CAS 1806367-58-7)
Recommended Standards
- Methyl 2-(2,6-dichloro-4-nitrophenyl)acetate (CAS 88135-25-5)
- Vildagliptin Impurity 47 (CAS CATO-C4X-110047)
- Ethyl 2,6-dichloro-3-nitrobenzoate (CAS 773137-11-4)
- Vildagliptin Impurity 73 (CAS 1811569-16-0)
- 7-bromo-3,3-dimethyl-2,3-dihydro-1H-indole (CAS 1260675-93-1)
- 3-(4-Acetamidobenzenesulfonamido)-3-(4-methylphenyl)propanoic acid (CAS 796084-48-5)
- 2-Amino-3-hydroxycyclopent-2-en-1-one hydrochloride (CAS 82659-07-2)
- Olopatadine Impurity 25 (CAS 18355-96-9)
- (E)-3-(dimethylamino)-1-(4-(phenylsulfinyl)phenyl)prop-2-en-1-one (CAS 321432-56-8)
- (4S,5R)-N-(4-Bromophenyl)-3-oxo-4,5-diphenylpyrazolidine-1-carboxamide (CAS 147523-65-7)
- 4-(4-Bromobenzyl)thiomorpholine (CAS 17494-28-9)
- VOC Internal Standard Solution (CAS CATO-MCHM701326-ME)
- (3,4-Dichloro-benzylamino)-acetic acid (CAS 261959-65-3)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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