2-(4-Amidinophenyl)indole-6-carboxamidine Dihydrochloride 2-(4-Carbamimidoylphenyl)indole-6-carboximidamide Dihydrochloride 28718-90-3 4',6-Diamidino-2-phenylindole Dihydrochloride A2412 DAPI.2HCl CAS 28718-90-3
| CAS No. | 28718-90-3 |
| Molecular Formula | C16H29N5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-Amidinophenyl)indole-6-carboxamidine Dihydrochloride 2-(4-Carbamimidoylphenyl)indole-6-carboximidamide Dihydrochloride 28718-90-3 4',6-Diamidino-2-phenylindole Dihydrochloride A2412 DAPI.2HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(4-Amidinophenyl)indole-6-carboxamidine Dihydrochloride 2-(4-Carbamimidoylphenyl)indole-6-carboximidamide Dihydrochloride 28718-90-3 4',6-Diamidino-2-phenylindole Dihydrochloride A2412 DAPI.2HCl (CAS 28718-90-3) is a high-purity analytical reference standard with the molecular formula C16H29N5HCl and a molecular weight of 327.90 g/mol.
The molecular framework of 2-(4-Amidinophenyl)indole-6-carboxamidine Dihydrochloride 2-(4-Carbamimidoylphenyl)indole-6-carboximidamide Dihydrochloride 28718-90-3 4',6-Diamidino-2-phenylindole Dihydrochloride A2412 DAPI.2HCl (C16H29N5HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H29N5 2*HCl |
| Molecular Weight | 327.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
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- (2E)-3-(3-Chlorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 52182-34-0)
- (1R,2S,5S,6S)-3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid (CAS 159262-32-5)
- 7-Bromothiochroman-4-ol (CAS 13735-27-8)
- 2-((1-(3-Chloro-4-methylphenyl)-1H-tetrazol-5-yl)thio)-N-isopropylacetamide (CAS 874467-78-4)
- 4-Bromo-2-{[(3,5-dichlorophenyl)amino]methyl}-6-methoxyphenol (CAS 329779-01-3)
- 2-(2-Bromo-4-chlorophenoxy)cyclopentan-1-one (CAS 1234845-07-8)
- 5-Boc-4,5,6,7-tetrahydrofuro[3,2-c]pyridine (CAS 179060-34-5)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
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