4-(4-(Chloromethyl)thiazol-2-yl)phenol CAS 287197-73-3
| CAS No. | 287197-73-3 |
| Molecular Formula | C10H8ClNOS |
| Molecular Weight | 225.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(4-(Chloromethyl)thiazol-2-yl)phenol (CAS 287197-73-3), a certified reference material (molecular formula C10H8ClNOS, MW 225.69 g/mol) for analytical method development and quality control.
Structurally, 4-(4-(Chloromethyl)thiazol-2-yl)phenol (C10H8ClNOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 225.69 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNOS |
| Molecular Weight | 225.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-Chloro-N-methylbenzo[b]thiophene-2-carboxamide (CAS 299929-76-3)
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- 3-Chloro-6-methylbenzo[b]thiophene-2-carboxamide (CAS 34586-87-3)
- 1-methanesulfonylpiperidine-4-carbonyl chloride 241138-40-9 4-(Chlorocarbonyl)-1-(methylsulphonyl)piperidine (CAS 241138-40-9)
- Naphthalene, 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethyl- (CAS 2084-69-7)
- Ethyl 2-{[4-(4-methoxyphenyl)-1,3-thiazol-2-yl][4-(trifluoromethyl)phenyl]amino}acetate (CAS 860784-12-9)
- 4-(Propan-2-yl)-2-(pyrrolidin-2-yl)-1,3-oxazole dihydrochloride (CAS 2097897-75-9)
- 2-(1H-Indol-3-yl)-N-(4-(methylthio)benzyl)ethanamine (CAS 355382-72-8)
- 3-chloro-2-hydroxypropyl dihydrogen phosphate (CAS 56729-01-2)
- 1-((2,5-Dimethylphenyl)sulfonyl)piperidin-4-one (CAS 1018581-06-0)
- 4-(Bromomethyl)-6-chloro-3,4'-bipyridine (CAS 1227515-73-2)
- 2-Chloro-n-[5-(dimethylsulfamoyl)-2-methoxyphenyl]propanamide (CAS 1155000-26-2)
- methyl 5-chloro-1H-imidazole-2-carboxylate (CAS 1211589-29-5)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
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