N-(4-Methylpyrimidin-2-yl)cyanamide CAS 28732-65-2
| CAS No. | 28732-65-2 |
| Molecular Formula | C10H14N4O4 |
| Molecular Weight | 254.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-Methylpyrimidin-2-yl)cyanamide (C10H14N4O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(4-Methylpyrimidin-2-yl)cyanamide (CAS 28732-65-2), molecular formula C10H14N4O4 and molecular weight 254.24 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Methylpyrimidin-2-yl)cyanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N4O4 |
| Molecular Weight | 254.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 4 |
Related N Standards
- Ethyl 4-((4-methylpyrimidin-2-yl)thio)-3-oxobutanoate (CAS 1170787-28-6)
- 2-(((6-Methylpyrimidin-4-yl)thio)methyl)imidazo[1,2-a]pyridine (CAS 1251575-02-6)
- 4-Methyl-2-[(4-methylpyrimidin-2-yl)disulfanyl]pyrimidine (CAS 1142-08-1)
- 2-((6-Methylpyrimidin-4-yl)thio)-1-(p-tolyl)ethanone (CAS 89991-24-2)
- Ethyl 1-(4-methylpyrimidin-2-yl)piperidine-4-carboxylate (CAS 1273680-69-5)
- 3-(((4-Methylpyrimidin-2-yl)thio)methyl)benzoic acid (CAS 679414-38-1)
- 2-(((2-Methylpyrimidin-5-yl)methyl)amino)-5-nitropyrimidin-4(1H)-one (CAS 77961-32-1)
- 1,4-Bis(2-methylpyrimidin-5-yl)benzene (CAS 193886-29-2)
Recommended Standards
- N-(3-Hydroxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 717828-52-9)
- n-(4-Nitrophenyl)-1h-1,3-benzodiazol-2-amine (CAS 26946-70-3)
- Methyl 9-oxo-9H-xanthene-1-carboxylate (CAS 85636-86-8)
- N-(4-Oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-2-yl)benzamide (CAS 88523-00-6)
- 2,6-Dimethoxy-4-{[(prop-2-en-1-yl)amino]methyl}phenol (CAS 1042588-29-3)
- Methyl 4-(benzo[d]thiazol-2-yl)butanoate (CAS 100192-34-5)
- Methyl 5-phenyl-3,4-dihydro-2H-pyrrole-2-carboxylate (CAS 111836-35-2)
- 4,5-Dimethyl-6-(methylthio)pyridazin-3-amine (CAS 1402609-42-0)
- 1,2-Dimethylcyclohexane-1-carboxylic acid (CAS 7112-19-8)
- Altretamine (CAS 645-05-6)
- 5-Chloro-4-(piperazin-1-yl)pyridine-3-sulfonamide (CAS 1352531-15-7)
- 2-(4-Isopropoxyphenyl)quinoline-4-carboxylic acid (CAS 425373-14-4)
- 4-Methoxy-1-methyl-1H-indole-3-carbaldehyde (CAS 620175-74-8)
- [pGlu] Semaglutide (CAS CATO-C4X-2226288)
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