Moxifloxacin Impurity 16 CAS 28749-88-4
| CAS No. | 28749-88-4 |
| Molecular Formula | C8H3F3O5 |
| Molecular Weight | 236.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Moxifloxacin Impurity 16 (CAS 28749-88-4) is a certified pharmaceutical impurity reference standard with the molecular formula C8H3F3O5 and a molecular weight of 236.10 g/mol.
Based on its molecular formula C8H3F3O5, Moxifloxacin Impurity 16 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 236.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Moxifloxacin Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3F3O5 |
| Molecular Weight | 236.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F-containing |
Related Moxifloxacin Standards
- Moxifloxacin Impurity N39 (CAS 1824286-08-9)
- Moxifloxacin Impurity 70 (CAS 133492-64-5)
- Moxifloxacin Impurity 114 (CAS 652-03-9)
- Moxifloxacin Impurity 64 (CAS 18184-75-3)
- Moxifloxacin Impurity N41 (CAS 172602-81-2)
- Moxifloxacin impurity 160 (CAS 1415319-29-7)
- Moxifloxacin Impurity 95 (CAS 71083-22-2)
- Moxifloxacin Impurity 55 (CAS 53764-99-1)
Recommended Standards
- 3,5-Dinitrobenzotrifluoride (CAS 401-99-0)
- Rivaroxaban Impurity 70 (CAS 1384257-81-1)
- 3,5-Dichloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-amine (CAS 2450343-45-8)
- 3,6-Dichloro-9H-Carbazole (CAS 5599-71-3)
- Trifarotene impurity 19 (CAS CATO-C4X-313219)
- Alanyl Glutamine Impurity 4 (CAS CATO-C4X-19744)
- Flunarizine Impurity 14 (CAS CATO-C4X-135714)
- 1-Carbamoyl-2,3-dihydro-1h-indole-5-sulfonyl fluoride (CAS 1193387-46-0)
- 2-(5-Chlorothiophen-2-yl)-2-methoxyethan-1-amine (CAS 1250927-84-4)
- 1,3-Diethyl 2-({4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}methyl)-2-acetamidopropanedioate (CAS 439108-33-5)
- (3-Methoxybenzyl)boronic Acid Pinacol Ester (CAS 797762-23-3)
- 1-Methyl-5-aminomethylimidazole (CAS 486414-86-2)
- 2-((3-Cyano-4,6-dimethylpyridin-2-yl)thio)acetamide (CAS 328072-66-8)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
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