(e)-n'-((2,6-Dichloropyridin-4-yl)methylene)-2-(trifluoromethyl)benzenesulfonohydrazide CAS 287917-80-0
| CAS No. | 287917-80-0 |
| Molecular Formula | C13H8Cl2F3N3O2S |
| Molecular Weight | 398.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(e)-n'-((2,6-Dichloropyridin-4-yl)methylene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 287917-80-0), molecular formula C13H8Cl2F3N3O2S and molecular weight 398.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (e)-n'-((2,6-Dichloropyridin-4-yl)methylene)-2-(trifluoromethyl)benzenesulfonohydrazide (C13H8Cl2F3N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (e)-n'-((2,6-Dichloropyridin-4-yl)methylene)-2-(trifluoromethyl)benzenesulfonohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2F3N3O2S |
| Molecular Weight | 398.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
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- 3-(1,2,2-Triphenylvinyl)benzaldehyde (CAS 2138330-46-6)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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