Fluconazole Impurity 21 CAS 288-36-8
| CAS No. | 288-36-8 |
| Molecular Formula | C2H3N3 |
| Molecular Weight | 69.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluconazole Impurity 21.
Fluconazole Impurity 21 (CAS 288-36-8) is a certified pharmaceutical impurity reference standard with the molecular formula C2H3N3 and a molecular weight of 69.07 g/mol.
Fluconazole Impurity 21 (C2H3N3) contains a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C2H3N3 |
| Molecular Weight | 69.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Fluconazole Standards
- Fluconazole Impurity 44 (CAS 6086-21-1)
- Fluconazole Impurity 53 (CAS CATO-C4X-101953)
- Fluconazole Impurity 62 (CAS CATO-C4X-101962)
- Fluconazole Impurity 18 (CAS 5201-50-3)
- Fluconazole Impurity 54 (CAS CATO-C4X-101954)
- Fluconazole Impurity 68 (CAS CATO-C4X-101968)
- Fluconazole Impurity 70 (CAS 70890-80-1)
- Fluconazole Impurity 35 (CAS CATO-C4X-101935)
Recommended Standards
- 4H-1,2,4-Triazole (CAS 63598-71-0)
- Sulbactam Impurity 22 (CAS 288-35-7)
- 1H-1, 2, 4 Triazole (CAS 736917-78-5)
- 1 H-1,2,4-Triazole (CAS 288-88-0)
- Etoricoxib Impurity 78 (CAS 99055-63-7)
- Dexmedetomidine Impurity 67 (CAS 847829-38-3)
- Allopurinol impurity 13 (CAS CATO-C4X-145813)
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