Ticagrelor Impurity 190 CAS 2880337-24-4
| CAS No. | 2880337-24-4 |
| Molecular Formula | C23H28F2N6O4S |
| Molecular Weight | 522.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 522.57 g/mol gives Ticagrelor Impurity 190 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ticagrelor Impurity 190 (CAS 2880337-24-4) is a certified pharmaceutical impurity reference standard with the molecular formula C23H28F2N6O4S and a molecular weight of 522.57 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Ticagrelor Impurity 190 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 522.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 190 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H28F2N6O4S |
| Molecular Weight | 522.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 14 (CAS 1808068-84-9)
- Ticagrelor (CAS 274693-27-5)
- Ticagrelor Impurity 1 (CAS 2096989-55-6)
- Ticagrelor Impurity 182 (CAS CATO-C4X-1093182)
- Ticagrelor Impurity 183 (CAS CATO-C4X-1093183)
- Ticagrelor Impurity 189 (CAS CATO-C4X-1093189)
- Ticagrelor Impurity 191 (CAS CATO-C4X-1093191)
- Ticagrelor Impurity 2 (CAS 2435586-30-2)
Recommended Standards
- Ticagrelor Impurity 3 (CAS 2096989-56-7)
- Ticagrelor Impurity 33 (CAS CATO-C4X-109333)
- Ticagrelor Impurity 36 (CAS CATO-C4X-109336)
- Ticagrelor EP Impurity B (CAS 1788033-05-5)
- Triamcinolone Acetonide Impurity 50 (CAS CATO-C4X-132650)
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