1-Boc-4-(Cbz-amino)-3-pyrrolidinone CAS 288083-67-0

Purity 97%+In StockPharmaceutical Standards
CAS No.288083-67-0
Molecular FormulaC17H22N2O5
Molecular Weight334.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Boc-4-(Cbz-amino)-3-pyrrolidinone CAS 288083-67-0 chemical structure

Description

The occurrence of 1-Boc-4-(Cbz-amino)-3-pyrrolidinone is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-Boc-4-(Cbz-amino)-3-pyrrolidinone (CAS 288083-67-0) is a high-purity analytical reference standard with the molecular formula C17H22N2O5 and a molecular weight of 334.37 g/mol.

The molecular framework of 1-Boc-4-(Cbz-amino)-3-pyrrolidinone (C17H22N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC17H22N2O5
Molecular Weight334.37 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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