3-(tert-Butyl)-5-chloro-6-methyldihydropyrimidine-2,4(1H,3H)-dione CAS 288154-80-3
| CAS No. | 288154-80-3 |
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(tert-Butyl)-5-chloro-6-methyldihydropyrimidine-2,4(1H,3H)-dione (CAS 288154-80-3), molecular formula C9H15ClN2O2 and molecular weight 218.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 3-(tert-Butyl)-5-chloro-6-methyldihydropyrimidine-2,4(1H,3H)-dione is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 3-(tert-Butyl)-5-chloro-6-methyldihydropyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-(4-Chlorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole (CAS 400077-07-8)
- 3-chloro-1,6-naphthyridine-7-carboxylic acid (CAS 2250243-66-2)
- 3-(3-Chloropropanoyl)-1-cyclopentylurea (CAS 949791-72-4)
- 3-Chloro-4-methoxy-1,1'-biphenyl (CAS 21424-83-9)
- 0104AD 1185025-66-4 3-(3-Chloro-4-fluorophenoxy)pyrrolidine hydrochloride C10H12Cl2FNO (CAS 1185025-66-4)
- (1-(Pyrimidin-4-yl)azetidin-3-yl)methanamine (CAS 1497802-78-4)
- 2-Amino-4-(4-isopropylphenyl)thiazole (CAS 108481-92-1)
- 4-(Methylsulfanyl)butanoic acid (CAS 32391-97-2)
- 4-(Methylamino)tetrahydro-2H-thiopyran1,1-dioxidehydrochloride (CAS 1268991-10-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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