2-Methoxy-6-methylpyrazine CAS 2882-21-5
| CAS No. | 2882-21-5 |
| Molecular Formula | C6H8N2O |
| Molecular Weight | 124.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Methoxy-6-methylpyrazine (CAS 2882-21-5), molecular formula C6H8N2O and molecular weight 124.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Methoxy-6-methylpyrazine (C6H8N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Methoxy-6-methylpyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O |
| Molecular Weight | 124.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 2-Methoxy-4-methylpyrimidine (CAS 14001-60-6)
- 3-Methoxy-6-methylpyridazine (CAS 17644-83-6)
- 2-Methoxy-5-methylpyrimidine (CAS 17758-07-5)
- 4-Methoxy-5-methylpyrimidine (CAS 17758-12-2)
- 5-Methoxy-2-methylpyrimidine (CAS 1782399-94-3)
- 5-Methoxy-4-methylpyrimidine (CAS 19175-07-6)
- 2-Methoxy-3(or 5)-methylpyrazine (CAS 68378-13-2)
- 2-Methoxy-5-methylpyrazine (CAS 2882-22-6)
Recommended Standards
- 2-Methyl-1H-pyrrole-3-carboxamide (CAS 67464-88-4)
- 2-Methyl-5,6-dihydro-4H-pyrrolo[3,4-d]oxazole (CAS 885273-92-7)
- 2-Hydroxyisonicotinonitrile (CAS 94805-51-3)
- 2-Methyl-5-oxopyrrolidine-2-carbonitrile (CAS 86240-21-3)
- Asenapine Impurity 7 (CAS 70958-18-8)
- 4-Bromo-N-1-butyl-N-1-methyl-1,2-benzenediamine (CAS 1017032-76-6)
- 3-Bromo-6-methyl-1H-indazol-4-amine (CAS 885520-95-6)
- 4-Chloro-2-methyl-6-(methylamino)pyrimidine-5-carbaldehyde (CAS 1499972-46-1)
- Phenyl 3-oxobutanoate (CAS 6864-62-6)
- 3-(4-amino-3-methoxyphenyl)prop-2-enoic acid (CAS 104274-20-6)
- N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)propionamide (CAS 102908-66-7)
- 4-isopropyl-7-methoxy-benzofuran-2-carboxylic acid (CAS 2490417-95-1)
- 6,8-Dibromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one (CAS 1305325-17-0)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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