5-Methyl-1-(4-methylphenyl)-1h-pyrazole-4-carboxylic acid CAS 288251-47-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Methyl-1-(4-methylphenyl)-1h-pyrazole-4-carboxylic acid.

5-Methyl-1-(4-methylphenyl)-1h-pyrazole-4-carboxylic acid (CAS 288251-47-8) is a high-purity analytical reference standard with the molecular formula C12H12N2O2 and a molecular weight of 216.24 g/mol.

The molecular framework of 5-Methyl-1-(4-methylphenyl)-1h-pyrazole-4-carboxylic acid (C12H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Methyl-1-(4-methylphenyl)-1h-pyrazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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