Ethyl 1-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylate CAS 288251-64-9
| CAS No. | 288251-64-9 |
| Molecular Formula | C13H13FN2O2 |
| Molecular Weight | 248.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 248.25 g/mol gives Ethyl 1-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 1-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylate (CAS 288251-64-9), molecular formula C13H13FN2O2 and molecular weight 248.25 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 1-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylate (C13H13FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 1-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13FN2O2 |
| Molecular Weight | 248.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 1-(3-fluorophenyl)-5-propyl-1H-pyrazole-4-carboxylic acid (CAS 1003748-66-0)
- 1-(4-Fluorophenyl)-5-(propan-2-yl)-1h-pyrazole-4-carboxylic acid (CAS 1152975-63-7)
- 3-(3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl)propanoic acid (CAS 1215981-64-8)
- Ethyl 4-(4-fluorophenyl)-3-methyl-1H-pyrazole-5-carboxylate (CAS 1341198-45-5)
- Ethyl 5-[(2-fluorophenyl)methyl]-1h-pyrazole-4-carboxylate (CAS 1580482-90-1)
- (E)-[(4-Fluorophenyl)methoxy][1-(5-methyl-1,2-oxazol-4-yl)ethylidene]amine (CAS 478049-28-4)
- 1-(4-fluorophenyl)-5-propyl-1H-pyrazole-4-carboxylic acid (CAS 924644-70-2)
- 2-(3-Fluorophenyl)tetrahydroimidazo[1,5-a]pyridine-1,3(2H,5H)-dione (CAS 60725-62-4)
Recommended Standards
- Ethyl 1-(2-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate (CAS 618092-38-9)
- Ethyl 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylate (CAS 288252-73-3)
- Dibenzo[b,d]furan-2-sulfonic acid (CAS 83863-63-2)
- Ethyl 2-{[(1Z)-2-cyano-2-(4-fluorophenyl)eth-1-en-1-yl]amino}acetate (CAS 478249-05-7)
- N-(4-(dimethylamino)phenyl)methacrylamide (CAS 2918-68-5)
- 4-(3,4-Dichlorophenyl)-N-(o-tolyl)piperazine-1-carboxamide (CAS 892799-23-4)
- 4-Methyl-3H-spiro[isobenzofuran-1,4'-piperidine] hydrochloride (CAS 1774897-61-8)
- Fingolimod Impurity 13 (CAS 162358-08-9)
- Ethyl 6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylate (CAS 1160474-53-2)
- 3-(3-chlorophenyl)cyclohexan-1-amine hydrochloride (CAS 1909312-80-6)
- 2-(4-Chlorophenyl)-4-(2,3-dichloro-4-(ethylsulfonyl)phenyl)thiazole (CAS 672951-37-0)
- 5-(4-Ethylphenyl)-5-oxovaleric acid (CAS 34670-04-7)
- 2-Bromo-5-ethylpyridine (CAS 19842-08-1)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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