1-(4-Fluorophenyl)-1h-pyrrole-2-carboxylic acid CAS 288251-67-2
| CAS No. | 288251-67-2 |
| Molecular Formula | C11H8FNO2 |
| Molecular Weight | 205.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorophenyl)-1h-pyrrole-2-carboxylic acid.
1-(4-Fluorophenyl)-1h-pyrrole-2-carboxylic acid (CAS 288251-67-2) is a high-purity analytical reference standard with the molecular formula C11H8FNO2 and a molecular weight of 205.19 g/mol.
1-(4-Fluorophenyl)-1h-pyrrole-2-carboxylic acid (C11H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Fluorophenyl)-1h-pyrrole-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8FNO2 |
| Molecular Weight | 205.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 102186-93-6 N-(2-Fluorophenyl)-1H-imidazole-5-carboxamide MFCD21648536 (CAS 102186-93-6)
- 5-(2-Fluorophenyl)-1-methyl-1H-1,2,4-triazole-3-carbaldehyde (CAS 1083401-17-5)
- 4-(2-Fluorophenyl)-1h-pyrrole-3-carboxylic acid (CAS 1096308-11-0)
- 1-(2-Fluorophenyl)-3-methyl-2,5-dihydro-1h-pyrrole-2,5-dione (CAS 1098352-14-7)
- 2-((4-Fluorophenyl)amino)pyrimidin-4(3H)-one (CAS 1201791-24-3)
- 1-(4-Fluorophenyl)-4-methyl-1H-1,2,3-triazole-5-carbaldehyde (CAS 136347-52-9)
- 1-(4-Fluorophenyl)-1H-imidazole-4-carboxamide (CAS 1427014-62-7)
- 5-(4-Fluorophenyl)-1H-pyrrole-2-carboxylic Acid (CAS 153783-33-6)
Recommended Standards
- 1-(4-Amino-3-fluorophenyl)pyrazin-2(1H)-one (CAS 863015-77-4)
- 1-(4-Fluorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione (CAS 66504-49-2)
- 1-(3-(4-Fluorophenyl)isoxazol-5-yl)ethanone (CAS 889938-97-0)
- 1-(4-Fluorophenyl)-3-methyl-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 883033-95-2)
- 2-((4-Methylpentan-2-yl)amino)propane-1,3-diol (CAS 1492842-71-3)
- 1310405-24-3 tert-Butyl 4-{2-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenoxy]ethyl}piperidine-1-carboxylate (CAS 1310405-24-3)
- 2-(2-(Methylthio)pyrimidin-4-yl)acetonitrile (CAS 897648-40-7)
- N-(3-Aminophenyl)-3-methylbenzamide (CAS 585517-66-4)
- 2-(Benzylthio)-4-(2-chlorophenyl)-6-(4-chlorophenyl)nicotinonitrile (CAS 332177-30-7)
- 1-Bromo-2,3-difluoro-4-(methoxymethyl)benzene (CAS 162744-57-2)
- 4-Allyl-2-chloropyridine (CAS 219727-28-3)
- 3-Amino-N-(4-chloro-phenyl)-4-methoxy-benzenesulfonamide (CAS 379255-10-4)
- (2E,4Z)-2,4-Decadienal (CAS 25152-83-4)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
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