Daprodustat impurity 1 CAS 2883118-63-4
| CAS No. | 2883118-63-4 |
| Molecular Formula | C16H26N2O4 |
| Molecular Weight | 310.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Daprodustat impurity 1 (CAS 2883118-63-4, C16H26N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H26N2O4, Daprodustat impurity 1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 310.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Daprodustat impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H26N2O4 |
| Molecular Weight | 310.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 2 |
Related Daprodustat Standards
- Daprodustat Impurity 45 (CAS CATO-C4X-240745)
- Daprodustat Impurity 13 (CAS 4833-41-4)
- Daprodustat impurity 2 (CAS CATO-C4X-24072)
- Daprodustat Impurity 20 (CAS CATO-C4X-240720)
- Daprodustat Impurity 46 (CAS CATO-C4X-240746)
- Daprodustat impurity 6 (CAS CATO-C4X-24076)
- Daprodustat Impurity 31 (CAS CATO-C4X-240731)
- Daprodustat Impurity 38 (CAS CATO-C4X-240738)
Recommended Standards
- Niraparib Impurity 29 (CAS 2308483-85-2)
- Meclofenoxate Impurity 4 (CAS CATO-C4X-24694)
- Dienogest Impurity 19 (CAS 7291-52-3)
- 1-Benzyl-4-(phenylamino)piperidine-4-carboxylicacid (CAS 85098-64-2)
- Clascoterone Impurity 6 (CAS CATO-C4X-33316)
- Atrasentan Impurity 134 (CAS 1058349-07-7)
- Norfloxacin Impurity 32 (CAS 70032-16-5)
- (S)-Ethyl 2-amino-3-phenylpropanoate (CAS 1795-96-6)
- 2-(4-Aminopiperidin-1-yl)-N-butyl-N-ethylacetamide (CAS 1513839-62-7)
- Methylene blue Impurity 17 (CAS CATO-C4X-189617)
- 2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)thiazole (CAS 2223035-84-3)
- 2-Amino-N-((2-chlorothiazol-5-yl)methyl)-N-methylacetamide (CAS 1353947-60-0)
- (R)-3-Amino-2-(3-phenoxyphenyl)propan-1-ol (CAS 1213481-27-6)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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