Methyl 4-amino-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-chloronicotinate CAS 2883421-70-1
| CAS No. | 2883421-70-1 |
| Molecular Formula | C15H25ClN2O4Si |
| Molecular Weight | 360.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-amino-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-chloronicotinate.
Methyl 4-amino-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-chloronicotinate (CAS 2883421-70-1) is a high-purity analytical reference standard with the molecular formula C15H25ClN2O4Si and a molecular weight of 360.91 g/mol.
The molecular framework of Methyl 4-amino-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-chloronicotinate (C15H25ClN2O4Si) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 4-amino-5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-chloronicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H25ClN2O4Si |
| Molecular Weight | 360.91 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 4-Amino-2,6-diiodophenol (CAS 2297-82-7)
- N-(3-Amino-4-chlorophenyl)-2-[2-(sec-butyl)-phenoxy]butanamide (CAS 1020054-76-5)
- N-(3-Amino-4-chlorophenyl)-4-(heptyloxy)benzamide (CAS 1020055-58-6)
- N-[6-Amino-1,2,3,4-tetrahydro-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-4-chloro-N-(2-methoxyethyl)butanamide (CAS 730949-94-7)
- 1-Amino-2-(4-chlorophenylazo)naphthalene-5-sulfonamide 118876-55-4 5-Amino-6-[(4-chlorophenyl)azo]-1-naphthalenesulfonamide 5-Amino-6-[2-(4-chlorophenyl)diazenyl]-1-naphthalenesulfonamide (CAS 118876-55-4)
- N-(6-amino-7-methoxyquinazolin-4-yl)-N-(3-chloro-4-fluorophenyl)acetamide (CAS 869199-62-2)
- (3-Amino-6-nitrobenzofuran-2-yl)(4-bromophenyl)methanone (CAS 351003-26-4)
- 6-Amino-2-(benzo[d][1,3]dioxol-5-ylmethyl)-4-bromoisoindolin-1-one (CAS 169043-96-3)
Recommended Standards
- 5-Chloro-N-((1-(2-methoxyethyl)piperidin-4-yl)methyl)-2-methylbenzenesulfonamide (CAS 953143-28-7)
- 3,5-Diiodo-4-methoxypyridine (CAS 849359-56-4)
- 3-bromo-2-fluoro-4-hydroxy-5-iodobenzoic acid (CAS 2770534-72-8)
- 3,5-Diiodo-4-methyl-1H-pyrrole-2-carbaldehyde (CAS 49569-09-7)
- 1-(Methylsulfinyl)-4-(methylthio)-6,7-dihydro-5H-cyclopenta[d]pyridazine (CAS 112740-87-1)
- N1,N1-diethyl-N2-(1-ethylpiperidin-4-yl)ethane-1,2-diamine (CAS 626217-94-5)
- t-Butyl acetate-PEG2-CH2COOH (CAS 883564-93-0)
- 2-(4-Phenyl-2-(p-tolylimino)thiazol-3(2H)-yl)ethan-1-ol (CAS 905784-36-3)
- 3-(3,5-Dimethylphenyl)-2-fluoropropiophenone (CAS 898780-82-0)
- 2-((1-(4-Hydroxyphenyl)-2,5-dioxopyrrolidin-3-yl)thio)nicotinic acid (CAS 924873-64-3)
- 1-(3-Nitrophenyl)pyridin-1-ium chloride (CAS 147308-71-2)
- 4-({[(3,4-dichlorophenyl)sulfonyl]amino}methyl)benzoic acid (CAS 790272-17-2)
- Methyl 2-(9H-pyrido[3,4-b]indole-1-carbonyl)benzoate (CAS 927210-41-1)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com