4-fluoro-1H-indol-5-ol CAS 288386-04-9
| CAS No. | 288386-04-9 |
| Molecular Formula | C8H14FNO |
| Molecular Weight | 159.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-fluoro-1H-indol-5-ol.
CATO supplies 4-fluoro-1H-indol-5-ol (CAS 288386-04-9), a certified reference material (molecular formula C8H14FNO, MW 159.20 g/mol) for analytical method development and quality control.
The molecular framework of 4-fluoro-1H-indol-5-ol (C8H14FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14FNO |
| Molecular Weight | 159.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluoro Standards
- 7-fluoro-1H-indazol-5-amine (CAS 1105175-07-2)
- 5-fluoro-1H-pyrrolo[2,3-b]pyridin-6-amine (CAS 1190321-94-8)
- 3-Fluoro-1-oxa-8-azaspiro[4.5]Decane (CAS 1214875-53-2)
- 5-fluoro-1H-indazol-6-amine (CAS 1360963-10-5)
- [trans-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methanol (CAS 1788873-66-4)
- 7-fluoro-1H-indazol-6-amine (CAS 1892745-85-5)
- (8-Fluoro-6-azaspiro[3.4]Octan-8-yl)methanol (CAS 2219375-02-5)
- 2-(5-fluoro-6-methylpyridin-2-yl)acetaldehyde (CAS 2306268-14-2)
Recommended Standards
- 4-fluoro-1H-indazol-7-amine (CAS 866144-03-8)
- 4-fluoro-1H-pyrrolo[2,3-b]pyridin-5-amine (CAS 651744-35-3)
- 3-Fluoro-1-oxa-7-azaspiro[4.5]Decane (CAS 2168335-03-1)
- 6-fluoro-1H-indol-4-ol (CAS 885521-04-0)
- (S)-2-Amino-3-methoxypropanoic acid (CAS 32620-11-4)
- 3-Methyl-4-(trifluoromethoxy)picolinonitrile (CAS 886372-31-2)
- 4-(4-amino-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenol (CAS 929974-65-2)
- (E)-(2-((hydroxyimino)methyl)phenyl)boronic acid (CAS 859160-67-1)
- rac-trans 3’-Hydroxymethylnicotine Hemisuccinate (CAS 1207282-59-4)
- Atomoxetine EP Impurity A HCl ((R)-Isomer) (CAS 1212215-97-8)
- (S)-4-Amino-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol (CAS 746584-77-0)
- 2-Methylquinoline-5-carbohydrazide (CAS 1144503-60-5)
- p-Coumaroylspermine (CAS 130210-35-4)
- Peptide T (CAS 106362-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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