2-Chloro-1H-benzimidazole-5-carboxaldehyde CAS 288579-82-8
| CAS No. | 288579-82-8 |
| Molecular Formula | C8H5ClN2O |
| Molecular Weight | 180.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-1H-benzimidazole-5-carboxaldehyde (CAS 288579-82-8), molecular formula C8H5ClN2O and molecular weight 180.59 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-1H-benzimidazole-5-carboxaldehyde (C8H5ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-Chloro-1H-benzimidazole-5-carboxaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O |
| Molecular Weight | 180.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 2-Chloro-1-benzofuran-3-carbaldehyde (CAS 79091-27-3)
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- 2-(4-Chlorophenyl)-1,3,4-oxadiazole (CAS 23289-10-3)
- 2-Chloro-1H-pyrrolo[2,3-c]pyridine-3-carbaldehyde (CAS 847801-92-7)
- 1-(Sec-butyl)cyclopropane-1-carboxylic acid (CAS 1542349-76-7)
- 2,7-Diaminodibenzo[b,e][1,4]dioxine (CAS 71400-35-6)
- 3-(1,3-Benzothiazol-2-yl)pyrazin-2-amine (CAS 1340259-98-4)
- (d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (CAS 114056-26-7)
- tert-Butyl (2S,4S)-2-methyl-4-(((trifluoromethyl)sulfonyl)oxy)pyrrolidine-1-carboxylate (CAS 2833709-35-4)
- 6-(Pyrrolidin-1-yl)hexan-2-amine (CAS 1248063-30-0)
- 2-(1,3-Dioxolan-2-ylmethyl)anisole 2-(1,3-dioxolan-2-ylmethyl)-1-methoxybenzene 842123-92-6 (CAS 842123-92-6)
- N-benzyl-6-chloro-N-ethylpyridazin-3-amine (CAS 1094315-96-4)
- 4-Methyloxazole-5-acetonitrile (CAS 98197-76-3)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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