8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide CAS 288861-42-7

Purity 97%+In StockPharmaceutical Standards
CAS No.288861-42-7
Molecular FormulaC18H17NO4
Molecular Weight311.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide CAS 288861-42-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 311.33 g/mol gives 8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide (CAS 288861-42-7), molecular formula C18H17NO4 and molecular weight 311.33 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide (C18H17NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H17NO4
Molecular Weight311.33 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1

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