3,5-Bis(benzyloxy)benzoyl Chloride CAS 28917-44-4
| CAS No. | 28917-44-4 |
| Molecular Formula | C21H17ClO3 |
| Molecular Weight | 352.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,5-Bis(benzyloxy)benzoyl Chloride (C21H17ClO3) is characterized by a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3,5-Bis(benzyloxy)benzoyl Chloride (CAS 28917-44-4), molecular formula C21H17ClO3 and molecular weight 352.81 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,5-Bis(benzyloxy)benzoyl Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H17ClO3 |
| Molecular Weight | 352.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
Related Bis Standards
- 3,4-Bis(benzyloxy)benzoyl chloride (CAS 1486-54-0)
- Methyl 4-[4-(benzyloxy)phenyl]-2-chlorobenzoate (CAS 1820687-92-0)
- Methyl 4-[3-(benzyloxy)phenyl]-2-chlorobenzoate (CAS 1820712-00-2)
- N-(benzyloxy)-3-iodobenzamide (CAS 1180850-00-3)
- 4-(Benzyloxy)-3-iodobenzamide (CAS 1706436-95-4)
- Methyl 5-(benzyloxy)-2-bromo-3,4-dihydroxybenzoate (CAS 848773-01-3)
- N-(benzyloxy)-2-iodobenzamide (CAS 22426-95-5)
- 2-(3-(Benzyloxy)-6-bromo-2-fluorophenyl)-1,3-dioxolane (CAS 2379321-63-6)
Recommended Standards
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-propyl-[1,2,4]triazolo[4,3-a]pyrimidin-7(8H)-one (CAS 891126-99-1)
- 4-[3-(4-Chlorophenyl)-4,5,6,7-tetrahydro-2H-indazol-2-yl]benzoic acid (CAS 861210-33-5)
- 3-(((4-Chlorophenyl)imino)methyl)-2-hydroxy-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinolin-4-one (CAS 338953-30-3)
- 5-Chloro-1-(4-methylbenzyl)-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide (CAS 400087-62-9)
- (3,6-Dichloropyridazin-4-yl)valine (CAS 1548121-99-8)
- 6-Fluoro-2-hydrazinyl-3-methylquinoline hydrochloride (CAS 1171668-88-4)
- N-(2-Butyl-1H-indol-5-yl)-4-methoxybenzenesulfonamide (CAS 919490-51-0)
- 3-Fluoro-n-methyl-5-nitrobenzamide (CAS 1239596-39-4)
- 3-Bromo-1,1,2-trifluoroprop-1-ene (CAS 178676-13-6)
- 2H,5H,6H-[1,3]dioxolo[4,5-g]quinazolin-6-one (CAS 98216-14-9)
- 3-Azabicyclo[3.3.1]nonan-7-ol (CAS 1314960-39-8)
- 2-(3-Formyl-1H-indol-1-yl)acetamide (CAS 312973-43-6)
- 4-Bromo-2-ethyl-2H-benzo[d][1,2,3]triazole (CAS 1783329-29-2)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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