5'-Fluoro-6'-(trifluoromethyl)-1'H-spiro[cyclopropane-1,4'-isoquinoline]-1',3'(2'H)-dione CAS 2892253-29-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2892253-29-9
Molecular FormulaC12H7F4NO2
Molecular Weight273.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5'-Fluoro-6'-(trifluoromethyl)-1'H-spiro[cyclopropane-1,4'-isoquinoline]-1',3'(2'H)-dione CAS 2892253-29-9 chemical structure

Description

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5'-Fluoro-6'-(trifluoromethyl)-1'H-spiro[cyclopropane-1,4'-isoquinoline]-1',3'(2'H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO supplies 5'-Fluoro-6'-(trifluoromethyl)-1'H-spiro[cyclopropane-1,4'-isoquinoline]-1',3'(2'H)-dione (CAS 2892253-29-9), a certified reference material (molecular formula C12H7F4NO2, MW 273.18 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H7F4NO2
Molecular Weight273.18 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Halogen ContentF-containing
Nitrogen Atoms1

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