Dextromethorphan Impurity 11 CAS 28973-48-0
| CAS No. | 28973-48-0 |
| Molecular Formula | C18H23NO2 |
| Molecular Weight | 285.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dextromethorphan Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Dextromethorphan Impurity 11 (CAS 28973-48-0, C18H23NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H23NO2, Dextromethorphan Impurity 11 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 285.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H23NO2 |
| Molecular Weight | 285.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 1 |
Related Dextromethorphan Standards
- Dextromethorphan Impurity 12 (CAS 51745-05-2)
- Dextromethorphan Impurity 14 (Mixture of Rotamers) (CAS 29144-31-8)
- Dextromethorphan Impurity 21 (CAS 51773-23-0)
- Dextromethorphan EP Impurity C (CAS 57969-05-8)
- Dextromethorphan Impurity 36 (CAS CATO-C4X-115736)
- Dextromethorphan Impurity 6 (CAS 1329834-01-6)
- Dextromethorphan Impurity 37 (CAS 2382909-24-0)
- Dextromethorphan Impurity 44 (CAS CATO-C4X-115744)
Recommended Standards
- Edoxaban Impurity 76 (CAS 365998-36-3)
- Edoxaban Impurity 47 (CAS 2081883-52-3)
- Edoxaban Impurity 45 (CAS 2081883-50-1)
- Edoxaban Impurity 42 (CAS 2081883-53-4)
- Fudosteine Impurity 27 (CAS CATO-C4X-144727)
- Budesonide Impurity 18 (CAS CATO-C4X-138918)
- Aciclovir EP Impurity F (CAS 110104-37-5)
- 2-Bromo-N-(3-bromophenyl)acetamide (CAS 83276-95-3)
- tert-Butyl 3-vinyl-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate (CAS 2738870-34-1)
- 1-(2,6-Difluorophenyl)cyclopentanamine Hydrochloride (CAS 1896428-24-2)
- 20330-92-1 3-Chloro-N-(4-ethylphenyl)propanamide 6864AD C11H14ClNO (CAS 20330-92-1)
- (S)-2-amino-N-benzyl-N,3-dimethylbutanamide (CAS 179876-54-1)
- 2-Chloro-7-(trifluoromethyl)quinoxaline (CAS 883-94-3)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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