cis-2-(3,4-Difluorobenzoyl)cyclohexanecarboxylic acid CAS 289911-76-8
| CAS No. | 289911-76-8 |
| Molecular Formula | C14H14F2O3 |
| Molecular Weight | 268.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of cis-2-(3,4-Difluorobenzoyl)cyclohexanecarboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
cis-2-(3,4-Difluorobenzoyl)cyclohexanecarboxylic acid (CAS 289911-76-8) is a high-purity analytical reference standard with the molecular formula C14H14F2O3 and a molecular weight of 268.26 g/mol.
The molecular framework of cis-2-(3,4-Difluorobenzoyl)cyclohexanecarboxylic acid (C14H14F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures cis-2-(3,4-Difluorobenzoyl)cyclohexanecarboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14F2O3 |
| Molecular Weight | 268.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related cis Standards
- cis-2-(3,5-Difluorobenzoyl)cyclohexanecarboxylic acid (CAS 844856-71-9)
- 1-(2,4-Difluorobenzoyl)piperidine-4-carboxylic acid (CAS 700815-59-4)
- 4-(2,5-Difluorobenzoyl)isoquinoline (CAS 1187167-02-7)
- 1187167-07-2 4-(2,6-Difluorobenzoyl)isoquinoline MFCD13153054 (CAS 1187167-07-2)
- 4-(3,4-Difluorobenzoyl)isoquinoline (CAS 1187167-54-9)
- 4-(3,5-Difluorobenzoyl)isoquinoline (CAS 1187169-81-8)
- 4-(2,3-Difluorobenzoyl)quinoline (CAS 1706429-82-4)
- 4-(2,5-Difluorobenzoyl)quinoline (CAS 1706429-84-6)
Recommended Standards
- Adamantane-1,3,5-tricarboxylic acid (CAS 213274-89-6)
- 8-Methoxylchrysophanol (CAS 3300-25-2)
- Ethyl 2-(2-formyl-4,6-dimethoxyphenoxy)acetate (CAS 76322-08-2)
- 8-Hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one (CAS 40316-76-5)
- 9-Tricosene (CAS 52078-48-5)
- (4-Bromopentyl)benzene (CAS 65511-83-3)
- Methyl 2-ethyl-6-hydroxy-2,3-dihydrobenzofuran-2-carboxylate (CAS 653578-60-0)
- 3-(4-Fluorophenyl)thiazolidine-2,4-dione (CAS 51964-22-8)
- 8-Methoxy-2,3-dimethylquinolin-4(1H)-one (CAS 188758-79-4)
- 5-(1-Bromoethyl)-2,3-dihydro-1h-indene (CAS 75078-93-2)
- 3-Hydroxypyridine-2-sulfonic acid (CAS 88511-41-5)
- 3-((3-Chloro-4-methylphenyl)amino)-1-(3,4-dichlorophenyl)propan-1-one (CAS 724751-83-1)
- Everolimus Impurity 15（Z&Emixture） (CAS 147438-27-5 (E-Isomer）)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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