Ethyl 4-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-3-oxobutanoate CAS 290299-67-1
| CAS No. | 290299-67-1 |
| Molecular Formula | C14H13F3N2O3S |
| Molecular Weight | 346.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 4-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-3-oxobutanoate (CAS 290299-67-1), molecular formula C14H13F3N2O3S and molecular weight 346.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 4-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-3-oxobutanoate (C14H13F3N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ethyl 4-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-3-oxobutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13F3N2O3S |
| Molecular Weight | 346.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- tert-Butyl (3R,4S)-3-fluoro-4-(prop-2-yn-1-yloxy)piperidine-1-carboxylate (CAS 2785397-76-2)
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- 5-Methyl-3-[(2-oxo-2-phenylethyl)sulfanyl]-1,2-thiazole-4-carbonitrile (CAS 338418-03-4)
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