1-Boc-3-iodo-1H-indazole CAS 290368-00-2
| CAS No. | 290368-00-2 |
| Molecular Formula | C12H13IN2O2 |
| Molecular Weight | 344.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-Boc-3-iodo-1H-indazole (CAS 290368-00-2), a certified reference material (molecular formula C12H13IN2O2, MW 344.15 g/mol) for analytical method development and quality control.
Structurally, 1-Boc-3-iodo-1H-indazole (C12H13IN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 344.15 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13IN2O2 |
| Molecular Weight | 344.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Boc Standards
- 1-Boc-6-iodo-1H-indazole (CAS 1158767-35-1)
- 1-Boc-3-iodo-1H-pyrrolo[2,3-c]pyridine (CAS 1174038-59-5)
- Ethyl 4-iodo-1,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (CAS 1537883-72-9)
- (R)-3-Iodo-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1638522-98-1)
- 2-(4-Iodo-5-(3-methoxyphenyl)-1H-pyrazol-1-yl)ethanol (CAS 1708037-72-2)
- 3-Iodo-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyrazine (CAS 1956340-43-4)
- 1-(3-Iodo-4-methyl-phenyl)-5-methyl-hexahydropyrimidine-2,4-dione (CAS 1992936-01-2)
- 3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-ol (CAS 2066567-78-8)
Recommended Standards
- 10-Iodonaphtho[1,2-b]benzofuran (CAS 2271091-82-6)
- 2,4-Dichloro-N-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl)benzamide (CAS 477885-66-8)
- 3,4-Dichloro-N-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl)benzamide (CAS 477885-67-9)
- (3-(8-Amino-1-iodoimidazo[1,5-a]pyrazin-3-yl)cyclobutyl)methanol (CAS 867165-43-3)
- N-Desmethyl Phenyltoloxamine HCl (CAS 75859-72-2)
- 3-Amino-n,2-dimethylbenzamide (CAS 926254-13-9)
- Ethyl 5-(2-methoxy-2-oxoethoxy)-2-phenylbenzofuran-3-carboxylate (CAS 300826-24-8)
- (1S,4S,5S)-2-azabicyclo[2.2.1]Heptan-5-ol (CAS 1438269-31-8)
- Rifaximin EP Impurity B (CAS 13929-35-6)
- 1-Bromo-4-n-butoxylbenzene (CAS 39969-57-8)
- Methyl 4-amino-3-(4-chlorophenyl)-4-methylpentanoate (CAS 1482602-29-8)
- 1,1'-(Cyclopent-3-ene-1,1-diyl)diethanone (CAS 58920-76-6)
- 6-bromothieno[3,2-b]thiophene-5-carboxylic acid (CAS 2573123-41-6)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
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