4-(Bromomethyl)-2-chlorobenzoic acid CAS 290820-38-1
| CAS No. | 290820-38-1 |
| Molecular Formula | C8H6BrClO2 |
| Molecular Weight | 249.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Bromomethyl)-2-chlorobenzoic acid (CAS 290820-38-1), molecular formula C8H6BrClO2 and molecular weight 249.49 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Bromomethyl)-2-chlorobenzoic acid (C8H6BrClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Bromomethyl)-2-chlorobenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrClO2 |
| Molecular Weight | 249.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
Related Bromomethyl Standards
- 3-(Bromomethyl)-4-chlorobenzoic acid (CAS 1187237-82-6)
- 3-(Bromomethyl)-2-chlorobenzoic acid (CAS 89540-41-0)
- 5-(Bromomethyl)-2-chlorobenzoic acid (CAS 66658-57-9)
- 2-(Bromomethyl)-4-chloro-1-ethoxybenzene (CAS 1094411-26-3)
- 2-(bromomethyl)-1-chloro-3-ethoxybenzene (CAS 329980-82-7)
- 4-(Bromomethyl)-1-chloro-2-ethoxybenzene (CAS 247569-90-0)
- 5-(Bromomethyl)-undecane (CAS 85531-02-8)
- 1-(Bromomethyl)-1-isopropoxycycloheptane (CAS 1247100-16-8)
Recommended Standards
- 3-Chloro-2-hydroxyphenacyl bromide (CAS 84320-78-5)
- 4-Bromo-2-chloro-6-methylbenzoic Acid (CAS 877149-07-0)
- 3-Bromo-5-chloro-4-methylbenzoic acid (CAS 515135-60-1)
- 4-Bromo-2-chlorobenzhydrazide (CAS 206559-39-9)
- 3-Methyl-1-(4-methylquinolin-2-yl)-1H-pyrazol-5-amine (CAS 307342-03-6)
- 2,2-Difluoroaziridine (CAS 188018-70-4)
- Methyl (R)-2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate (CAS 56877-38-4)
- 2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1832580-83-2)
- 3-(2,6-Dichloropyrimidin-4-yl)oxazolidin-2-one (CAS 270929-43-6)
- Dotinurad Impurity 21 (CAS CATO-C4X-249421)
- 1-(3-Methoxypyridin-2-yl)cyclopropane-1-carboxylic acid (CAS 1439899-14-5)
- 2-(2-Methylpyridin-4-yl)ethan-1-ol (CAS 13959-37-0)
- 3,5-Dichloropyrazolo[1,5-a]pyrimidine (CAS 1823383-15-8)
- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com