5-Chlorobenzo[d]isothiazol-3(2h)-one 1,1-dioxide CAS 29083-16-7
| CAS No. | 29083-16-7 |
| Molecular Formula | C7H4ClNO3S |
| Molecular Weight | 217.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chlorobenzo[d]isothiazol-3(2h)-one 1,1-dioxide (CAS 29083-16-7), a certified reference material (molecular formula C7H4ClNO3S, MW 217.63 g/mol) for analytical method development and quality control.
5-Chlorobenzo[d]isothiazol-3(2h)-one 1,1-dioxide (C7H4ClNO3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chlorobenzo[d]isothiazol-3(2h)-one 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClNO3S |
| Molecular Weight | 217.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorobenzo Standards
- 4-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 3476-02-6)
- 6-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 46149-10-4)
- 7-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-Dioxide (CAS 89999-91-7)
- 2-Chlorobenzo[d]oxazole-4-sulfonamide (CAS 1806537-10-9)
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Why CATO?
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