(2R,3R,4R)-2-(Hydroxymethyl)pyrrolidine-1,3,4-triol CAS 290834-26-3
| CAS No. | 290834-26-3 |
| Molecular Formula | C5H11NO4 |
| Molecular Weight | 149.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2R,3R,4R)-2-(Hydroxymethyl)pyrrolidine-1,3,4-triol.
(2R,3R,4R)-2-(Hydroxymethyl)pyrrolidine-1,3,4-triol (CAS 290834-26-3), molecular formula C5H11NO4 and molecular weight 149.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carbohydrate-derived structure, an amide group, (2R,3R,4R)-2-(Hydroxymethyl)pyrrolidine-1,3,4-triol is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 149.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2R,3R,4R)-2-(Hydroxymethyl)pyrrolidine-1,3,4-triol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H11NO4 |
| Molecular Weight | 149.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2,4-Dihydroxyphenyl)acetonitrile (CAS 57576-34-8)
- (2R,3R,4R)-2-amino-3,4,5-trihydroxypentanal (CAS 22738-07-4)
- (1H-Pyrazolo[4,3-c]pyridin-4-yl)methanol (CAS 776268-15-6)
- (2R,3R,4S,5R)-3-Amino-5-(hydroxymethyl)tetrahydrofuran-2,4-diol (CAS 279673-11-9)
- 1H-Indole-3-acetyl chloride (CAS 50720-05-3)
- 2-(2-oxo-1,2-dihydro-1,7-naphthyridin-1-yl)acetaldehyde (CAS 959615-71-5)
- (2R,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((phosphonooxy)methyl)tetrahydrofuran-3-yl acetate (CAS 23701-96-4)
- Diphenyl((phenylsulfinyl)methyl)phosphine oxide (CAS 87762-75-2)
- Nebivolol (CAS 99200-09-6)
- 4-Hydroxy-3-iodobenzonitrile (CAS 2296-23-3)
- 5-(Chloromethyl)benzo[d]thiazole (CAS 1262889-04-2)
- 4,5-dimethylthiazole-2-carbaldehyde (CAS 74531-15-0)
- 4-Chloro-2,6,7-trimethyl-5,6,7,8-tetrahydroquinazoline (CAS 1935593-03-5)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
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