5-Bromo-2-(trimethylsilyl)pyridine CAS 291312-74-8
| CAS No. | 291312-74-8 |
| Molecular Formula | C8H12BrNSi |
| Molecular Weight | 230.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Bromo-2-(trimethylsilyl)pyridine (CAS 291312-74-8), molecular formula C8H12BrNSi and molecular weight 230.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, bromine substitution, 5-Bromo-2-(trimethylsilyl)pyridine is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12BrNSi |
| Molecular Weight | 230.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-4-(trimethylsilyl)pyridine (CAS 134391-66-5)
- 2-Bromo-5-(trimethylsilyl)pyridine (CAS 325958-97-2)
- 2-Bromo-6-(trimethylsilyl)pyridine (CAS 59409-80-2)
- 6'-bromo-1',2'-dihydrospiro[cyclopropane-1,3'-indole] (CAS 1379360-39-0)
- 9-Bromo-9-decenenitrile (CAS 951887-76-6)
- 5-Bromo-2,3-dihydro-1-benzothiophen-3-amine (CAS 1156173-02-2)
- 2-Bromo-4-methylbenzene-1-carbothioamide (CAS 1208076-70-3)
- 6-Bromo-2,3-dihydrobenzo[b]thiophen-3-amine (CAS 1392072-63-7)
Recommended Standards
- 5-Amino-2-(4-nitrophenyl)oxazole-4-carbonitrile (CAS 53657-73-1)
- 5-Phenyl-3-(trifluoromethyl)dihydrofuran-2(3H)-one (CAS 241819-52-3)
- 5-Amino-1-(3-nitropyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 956754-94-2)
- 6-(Trifluoromethyl)chromane-3-carbaldehyde (CAS 944904-01-2)
- Methyl 2-fluoro-3-methoxyacrylate (CAS 834883-98-6)
- 2,7-Dimethoxy-9-mesityl-10-methylacridinium tetrafluoroborate (CAS 2635339-81-8)
- N-Boc-1-(trans-4-ethynylcyclohexyl)methanamine (CAS 1932050-98-0)
- Pemafibrate Impurity 96 (CAS CATO-C4X-290396)
- 8-Bromo-2,6-dimethyl-1,4-dihydroquinolin-4-one (CAS 1153001-12-7)
- 3-(cyclopropyl(hydroxy)methyl)benzonitrile (CAS 1002750-36-8)
- 3-Hydroxy-4-methoxybenzenepropanol (CAS 57627-75-5)
- Dotinurad Impurity 63 (CAS CATO-C4X-249463)
- 2-(6-oxoheptyl)-2,3-dihydro-1H-isoindole-1,3-dione (CAS 71510-42-4)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
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